Regulating STING

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منابع مشابه

STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.

MPYS (also known as STING, MITA, and TMEM173) is a type I IFN stimulator that is essential for host defense against DNA virus infection and appears important in defense against certain bacteria. The in vivo significance and mechanisms by which MPYS mediates host defense against nonviral pathogens are unknown. Using an MPYS-deficient mouse (Tmem173()), we determined that, distinct from ...

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ژورنال

عنوان ژورنال: Nature Immunology

سال: 2013

ISSN: 1529-2908,1529-2916

DOI: 10.1038/ni.2799